Jul 11, 2023 | Patient News, Wellness
Summertime is prime time for ticks, which are becoming more prevalent each year. A combination of changing land use and warmer winters has greatly expanded the ticks’ habitat and they’re now found in more than half of U.S. counties. As a result, tick-borne Lyme disease has doubled over the last two decades to nearly 500,000 cases annually, earning it the unfortunate distinction of being the most common vector-borne illness in the Northern hemisphere. Read on for details on how to protect yourself this season, and in the summers to come.
Identifying Lyme
In its acute phase (one to two weeks after the bite), Lyme can cause fevers and chills, joint pain, headache, muscle aches and is frequently accompanied by a salmon-colored rash at the site of the tick bite. It may have a “bulls-eye” appearance, often considered a sign of infection, but the rash can manifest differently, or not at all. Diagnosis is based on symptoms, physical findings (e.g., rash), the possibility of exposure to infected ticks, and antibody tests. A high number of false negative tests occur in the early phase, however, because it takes time for the immune system to respond to the infection and create antibodies. As the infection progresses, virtually everyone with Lyme disease has a positive test result.
Treating early, late and long Lyme
Most people recover from Lyme disease rapidly and completely if diagnosed early and treated with a short course of oral antibiotics. More serious symptoms, including joint pain and swelling, nerve problems and neurological issues, may develop if Lyme disease is left untreated. Known as late Lyme disease, it can occur months to years after a tick bite, and requires a longer course of antibiotics, administered intravenously. Post-Treatment Lyme disease, sometimes called chronic or long Lyme disease, is experienced by 5% to 15% of patients who have lingering symptoms such as headache, fatigue, joint pain and “brain fog.” While the condition is not yet well understood, experts have found additional antibiotic treatments are not usually helpful, and the symptoms gradually resolve over time.
Preventing Lyme
The best way to avert the complications of Lyme disease is to vigilantly avoid ticks. These tips can help you prevent Lyme disease:
- Wear shoes, long pants tucked into socks, a long-sleeved shirt, hat and gloves in wooded or grassy areas.
- Stick to trails, stay clear of low bushes and long grass.
- Use insect repellants such as DEET, picardin, permethrin (apply to clothing).
- Do tick checks on your body after outside activities. Be sure to check your dogs for ticks
too!
- Remove any ticks promptly with clean, fine-tipped tweezers. Be reassured that just finding a tick on your skin doesn’t mean you’ll get Lyme disease; a tick needs to be attached for at least 48 hours before it can transmit the bacteria.
- Look for advanced protection in the next few years from two well-known names in vaccines – Pfizer and Moderna. An earlier vaccine, LYMERix, was discontinued in 2002 due to lack of interest at a time of lower Lyme disease cases, as well as concerns over side effects. Pfizer’s VLA15 is intended to block the bacteria from leaving the tick. Moderna is applying mRNA technology used in its COVID vaccine to target the Borrelia bacteria species at the root of most U.S. Lyme disease cases. Also of note is MassBiologics’ shot that delivers a single, human anti-Lyme antibody directly to a person to provide immediate immunity…now in trials.
QUICK BITES: Fast Facts About Lyme Disease
- Most Lyme disease infections in the U.S. occur May through September.
- Cases of Lyme disease are most commonly seen in the northeast and mid-Atlantic states
(from Maine to Virginia), the Midwest (Minnesota, Wisconsin, and Michigan), and the
West Coast (California).
- The disease was first recognized in Old Lyme, Connecticut in 1975 when a cluster of
children developed unexplained, rheumatoid arthritis-like symptoms. Not until the next decade was the cause discovered: the spiral bacteria Borrelia burdorferi in deer ticks prevalent in the forests near where the infections occurred. Testing confirmed the Lyme disease bacterium was passed to humans via the bite of a deer tick.
Sources: NIH, National Geographic
Oct 6, 2022 | Healthy Aging, Patient News, Wellness
Senior Moments Or Something More?
As Baby Boomers continue the inexorable journey deep into their senior years, preserving cognitive function understandably tops the list of worries. While Alzheimer’s Disease and related dementias are seen in just 5% of people over 65, that number jumps to 30% for people age 85 and over. Questions abound: is forgetting a name a sign of normal aging or an indicator of a more serious memory disorder? Are any nutritional supplements or pharmaceutical treatments available that are proven to stave off memory loss? Most importantly, what steps can be taken to modify individual risk?
To better understand how to identify and manage dementia and Alzheimer’s disease, we asked one of the country’s leading experts, R. Sean Morrison, MD, for his informed perspective on this growing concern for seniors, their families and caregivers. A practicing geriatrician, palliative medicine physician and health researcher for almost three decades, Dr. Morrison has earned numerous awards and recognition for his work, and currently serves as the Chair of the Brookdale Department of Geriatrics and Palliative Medicine at the Icahn School of Medicine at Mount Sinai and as Director of the Hertzberg Palliative Care Institute.
Is memory loss an inevitable, natural sign of aging?
Dr. Morrison: The good news is that not all cognitive functions decline with age. The ability to maintain attention, language comprehension, usage, and vocabulary does not decrease. Knowledge learned years ago like how to ride a bike, or brush your teeth, also stays intact. Additionally, when you learn something new and can remember it, you won’t forget it any more rapidly than when you were younger.
The not so good news is that it will take greater effort to learn those new things; more attention, repetition and use of memory-enhancing strategies will be needed. The ability to multitask is also diminished, as processing information takes longer and reaction times are slower. People may experience poorer performance when working under time pressure, and find it more difficult to manipulate information in the brain, such as calculating a tip in a restaurant or figuring out a route to travel from one place to another.
How do you distinguish between a “senior moment” lapse in memory and a sign of Alzheimer’s disease?
Dr. Morrison: So many people experience that temporary inability to remember a name. But if you are able to recall things with a cue or can pick it out from a list of possibilities, that’s evidence of a problem with retrieval but not with storage. You can be reassured that it doesn’t indicate Alzheimer’s disease but a “senior moment” because the information has been successfully stored in your memory.
Is routine screening for dementia recommended in older adults?
Dr. Morrison: The U.S. Preventive Services Task Force does not recommend for or against routine screening, saying no interventions are proven to have a significant effect in people with earlier detected cognitive impairment. However, it is required as part of Medicare’s yearly assessments, and most primary care physicians consider dementia screenings an essential part of their annual wellness exam.
What types of screening tests do you recommend?
Dr. Morrison: At least a dozen tests are available, each with their own benefits and drawbacks. I recommend the following for their ease of use and proven sensitivity and specificity in diagnosing cognitive impairment:
- Mini-Cog is a quick, three-minute evaluation. Patients are asked to repeat three words, draw a clock with hands at a specific time, and then recall the initial three words.
- Memory Impairment Screen assesses free and cued word recall. Patients are read four unrelated words from four categories (e.g. Red Cross, saucer, checkers, telegram) and after a few minutes of diversion, asked to recall the words in 20 seconds, either with no prompting or cued by category.
- Animal Fluency Test. Patients are asked to name as many animals as possible in a 60-second period.
Are there any risk factors for dementia and Alzheimer’s disease that can be controlled by patients?
Dr. Morrison: Quite a few risk factors are modifiable with lifestyle changes and non-pharmaceutical treatments. These include:
- Address hearing and visual impairments, with eyeglasses, hearing aids and other assistance
- Prevent and manage hypertension and diabetes
- Maintain a healthy weight
- Stop smoking
- Seek treatment for depression
- Prioritize regular exercise and physical activity
- Avoid social isolation
- Explore cognitive training
The best advice I can give to people in their 50s to 70s looking to prevent or delay progression of dementia and Alzheimer’s disease: exercise, exercise, exercise and rigorously control your blood pressure.
How are the symptoms frequently experienced by people with dementia – sleep disturbance, mood disorders, agitation – best addressed?
Dr. Morrison: There are a number of non-pharmaceutical interventions that have proven effective. Use adaptive clothing and assistive devices to help eliminate distress around bathing and dressing. Create a reassuring familiar structure to the day with a regular routine and activities. Optimize the sleep environment with a comfortable temperature, the right amount of light, a warm milky drink and a bath or shower before bed; avoid stimulating medications, drinks containing caffeine and alcohol, and exercise too close to bedtime. Pharmaceutical treatments can also be considered, including antidepressants to improve cognition and ameliorate agitation and aggression, and melatonin and melatonin antagonists to help with sleep disorders. Of note: medications such as benzodiazepines (BZD), non-BZD hypnotics, mood stabilizers and antipsychotics are no longer routinely recommended as side effects can outweigh possible benefits.
Are there any benefits to nutritional supplements or appetite stimulants?
Dr. Morrison: Nutritional supplements can help with weight gain in patients with anorexia or cachexia (‘wasting’ syndrome) but have no meaningful impact on survival. And while appetite stimulants such as cannabinoids and steroids are often given to help patients with dementia, there is no consistent data regarding their safety and efficacy.
What medications are available to treat or stop the progression of dementia?
Dr. Morrison: Until last year, only four medications were approved for treatment of dementia and Alzheimer’s disease, showing only a minimal to modest improvement in cognition. In 2021 a fifth drug was launched – aducanumab – a monoclonal antibody designed to reduce amyloid protein in the brain. Its fast-track approval was quite controversial as the clinical benefits of the drug were not proven during trials, which were stopped early as a result, and some severe side effects were observed. Interestingly, some researchers are now rethinking the idea that targeting amyloid protein plaques will eliminate Alzheimer’s disease, and instead exploring Alzheimer’s as a disease of inflammation. This could be the next fascinating line of research.
How a Memory is Made
Memory begins to form by giving attention to the information received through your senses. Anything that interferes with your ability to pay attention, such as hearing impairment, will affect the formation of a sensory memory. Successful integration of sensory memories into your working memory enables you to temporarily store, organize and manipulate information. These memories are then encoded into long-term memory and finally put into permanent storage.
Jul 8, 2022 | Patient News, Wellness
Stay Safe with Sunscreen, Sunglasses and Plenty of Water
The longer, sunshine filled days of summer are upon us and without a doubt, they are one of life’s unrivaled joys, especially when you protect yourself from the powerful impact of ultraviolet rays. With that in mind, we share our tips for safe summer fun; from choosing and using the right sunscreen to staying hydrated.
The debate around sunscreen safety heated up with last year’s recall of some popular consumer products containing chemicals such as benzene, which is absorbed through the skin and into the bloodstream. Yet according to the FDA, the American Academy of Dermatology and other experts, there is minimal evidence that systemic absorption of these ingredients is toxic or harmful to health. There is, however, a mountain of proof regarding the harmful effects of sunburn – most notably its significant contribution to the risk of melanoma.
“Use of a broad-spectrum, SPF 30 sunscreen effectively blocks UVB and UVA rays to prevent sunburn,” says Dr. Andrea Murina, MD, associate professor of dermatology at Tulane University School of Medicine and director of the University Medical Center’s dermatology clinics. “This not only reduces the risk of developing skin cancer but also decreases signs of early aging on your skin (such as wrinkles, age spots, sagging skin) and stops existing melasma from darkening and new patches from appearing.”
According to Dr. Murina, while we know some ingredients in sunscreen do cross over into the bloodstream, most are rated by the FDA as GRASE, meaning generally recognized as safe and effective.
A bit of background: Earlier studies conducted by the FDA showed that common chemical ingredients used in sunscreen, including oxybenzone are absorbed into the bloodstream.
Further research on whether systemic absorption of oxybenzone was an actual concern was suggested. However, no clear links to any health problems in humans were identified.
Nevertheless, the ingredient has been eliminated from most sunscreens currently being manufactured, making it easy to find an oxybenzone-free product.
When applied correctly, a water-resistant, SPF 30 sunscreen is optimal, blocking 97% of UVB rays. “A higher SPF is fine, but only incrementally blocks more rays, and the time and duration of effectiveness is the same,” says Murina.
The best way to protect yourself is by using a combination of measures:
- Wear sun-protective clothing, including a lightweight, loose-fitting, long-sleeved shirt, pants, a wide-brimmed hat and sunglasses. Darker colors, densely woven cloth, unbleached cotton and shiny polyesters are recommended by the Skin Cancer Foundation.
- Judiciously apply broad-spectrum sunscreen every two hours on uncovered body parts, such as top of hands, face, neck and ears.
- Swap out regular SPF 15 foundation for a tinted sunscreen. “There are so many cosmetically elegant ones available today that mimic the look of makeup but offer much more protection,” says Murina. Tinted sunscreens with an SPF of 30 or higher provide protection that blends well with all types of natural skin tones, and help prevent exposure to both UV rays and visible light from the sun.
- Seek shade when the sun’s rays are strongest, between 10:00 a.m. and 2:00 p.m.
Like sunscreen, sunglasses are vital in blocking the harmful effects of UV radiation. UVA and UVB rays can cause increased risk of conditions such as cataracts, eye cancers and growths on the eye, as well as premature aging of the delicate skin around your eye. Choose sunglasses that block 99% or 100% of all UV light or are listed as having UV absorption up to 400nm. Wear them even when it’s hazy or cloudy, as UV light can pass right through clouds. And although you’ve undoubtedly heard this piece of advice before, it bears repeating: To protect your retina, never look directly at the sun.
Finally, drink up when you’re out in the sun. Water is the elixir of choice, helping to lower your body temperature and replace the fluids you lose through sweating. This is particularly important for older adults whose body’s fluid reserve becomes smaller and thirst sense decreases as they age. Be aware of the most common signs of dehydration – lightheadedness, fatigue, dizziness, less frequent urination, dark-colored urine – and rehydrate promptly with cool water.
Safe Travels
If your summer vacation includes international travel, we recommend some healthy pre-planning that includes the following:
- COVID-19: Make sure you are up to date with your vaccines and boosters. Get tested for COVID-19 as close to the time of your departure as possible (no more than three days before travel). Do not travel if you have COVID-19 symptoms, if you tested positive or if you are in quarantine due to possible exposure.
- Check the U.S. Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO) websites for the most up-to-date travel alerts, advisories and recommendations. Immunizations needed will vary based on your health condition, immunization history, countries and regions on your itinerary, and duration of your visit.
- Update your routine immunizations to protect against increased risk of exposure to illnesses such as seasonal flu, diphtheria, varicella (chickenpox), measles, mumps and rubella. For quick guidance on additional immunizations you may need, try the online tool at GlobalTravEpiNet.
- To protect yourself from the serious diseases spread by mosquitos, such as dengue fever and malaria, bring an EPA-registered insect repellent with an active ingredient like DEET or picaridin.
- Pack your prescription medications and consider bringing over-the-counter medicines, including anti-diarrheal medicine, antacid, antihistamine, hydrocortisone cream, motion sickness medicine, cough medicine, pain and fever medicine, and mild laxative.
- Also, pack supplies to prevent illness or injury, such as hand sanitizer, water purification tablets, insect repellent and sunscreen; and first aid items such as antibacterial ointment, antiseptic wound cleanser, aloe gel, insect bite cream, a digital thermometer and bandages.
We encourage you to contact your health care provider four to six weeks prior to your trip for personalized guidance … and we wish you a safe and memorable journey!
Sources: FDA, American Academy of Dermatology, Mayo Clinic, American Academy of Ophthalmology, U.S. Centers for Disease Control and Prevention, Skin Cancer Foundation
